Graduate Programs Showcase

Interested in one of our graduate programs?
Join us ONLINE
Saturday, October 24 from 10 am - 12:30
for a sneek peek into your next best decision.

Schedule:
10 am - Welcome Remarks
10:10 - 10:40 am - Student Panel
10:45 - 11:15 am - Research Presentations
– Math Room
– Math Ed Room
11:20 am - 12:10 pm - Meet the Advisors
12:15 - 12:20 pm - Final remarks and slide show
$7M

In Active Grants

Explore our grants

Current Faculty Research

Math Happenings

Old Main staircase

Promotion from Associate Professor to Professor

Suho Oh

Old Main stairway

Promotion from Assistant Professor to Associate Professor & Tenure

Hamilton Hardison and Cody Patterson

Closeup of LBJ statue face

Promotion from Associate Professor of Instruction to Professor of Instruction

Bikai Nie and Amanda Walker

UAC Arch

Promotion from Assistant Professor of Instruction to Associate Professor of Instruction

Pritha Chakraborty, Jaroslaw Jaracz and Jackson Rebrovich

Students walking up the quad toward a statue of stallions

Promotion from Lecturer to Assistant Professor of Instruction

Hyun Chul Jang, Yichen Ma, Amy Lawrence-Wallquist, and Le Tran

@TXST Math

Upcoming Events

– until Oct. 15
Location:
DERR 238; 238
Cost:
Free
Contact:
Illona Weber
ih10@txstate.edu
Campus Sponsor:
Department of Mathematics
Math CATS is here to assist in almost all MATH courses for free!  If you're intimidated by the subject, come in and let's problem solve together.  Tutors are here to help reiterate, reinforce and help you relate to the content you heard in lecture. NO APPOINTMENT NEEDED! Click here for more information
more about event
– until Oct. 13
Location:
DERR 336; 336
Cost:
Free
Contact:
Cameron Farnsworth
clf129@txstate.edu
Campus Sponsor:
Department of Mathematics
Love a good problem?  Like to solve difficult puzzles?
Join professors, graduate students and undergraduates as we tackle problems presented from several mathematical journals.  An interest in higher level mathematics is all that is required to join our round table. Offer what you know, learn what you don't in a relaxed environment with some of our department's finest!
– until Oct. 16
Location:
DERR 238; 238
Cost:
Free
Contact:
Illona Weber
ih10@txstate.edu
Campus Sponsor:
Department of Mathematics
Math CATS is here to assist in almost all MATH courses for free!  If you're intimidated by the subject, come in and let's problem solve together.  Tutors are here to help reiterate, reinforce and help you relate to the content you heard in lecture. NO APPOINTMENT NEEDED! Click here for more information
more about event
–
Location:
DERR 333; 333
Cost:
Free
Contact:
Vera Ioudina
vi11@txstate.edu
Campus Sponsor:
Department of Mathematics
Breast cancer methylation age analysis with the incorporation of vital status and clinical information
Shuying Sun
Texas State University

Abstract: Breast cancer is associated with epigenetic changes such as DNA methylation and risk factors like
age, which itself is also linked to methylation changes. Previous studies have developed models to estimate
age from DNA methylation (DNAm age), such as the Horvath clock (with 353 CpG sites). Prior research has
used such clocks to analyze methylation in breast cancer. However, to our knowledge, no prior analysis has
considered patients’ vital status, and the original Horvath clock was not built with breast cancer-specific
clinical information such as hormone receptor status (ER and PR) or tumor stage in mind.
To address these gaps, we conducted a two-part DNAm age analysis using publicly available breast cancer
methylation data, stratified by vital status (Alive, Dead) and tissue type (Tumor, Matched Normal) into four
datasets: Alive Normal, Alive Tumor, Dead Normal, and Dead Tumor. In Part I, we examined relationships
between DNAm age, chronological age, clinical information and differentially methylated (DM) sites across
the four groups. In Part II, we built a regression model for each CpG site, with methylation level as the
response and chronological age, ER status, and PR status as covariates, and identified CpG sites where
methylation was significantly associated with age within each dataset. We further studied these sites and
their associated genes.
Our findings provide the first systematic comparison of DNAm age patterns between alive and dead breast
cancer patients. We show that vital status and clinical information are critical but previously overlooked axis
of variation in epigenetic aging analysis. This work offers a new understanding of DNAm age in breast cancer
and lays the groundwork for breast cancer-specific, vital-status-aware biomarkers for diagnosis, prognosis,
and treatment.
Click here for more information
more about event
– until Oct. 16
Location:
DERR 329; 329
Cost:
Free
Contact:
Ellen Couvillion
ebr21@txstate.edu
Campus Sponsor:
Department of Mathematics
TalkMath2Me is a seminar for students and by students organized by Pi Mu Epsilon. Talk Math 2 Me provides students, both graduate and undergraduate, an opportunity to present anything related to mathematics to an audience of their peers. The talks can be 15-90 minutes long. Past topics have included talks on impressive student research, famous mathematicians, sports, puzzles and games, and time travel! Click here for more information
more about event
– until Oct. 16
Location:
DERR 336; 336
Cost:
Free
Contact:
Logan Greenland
logan.greenland@txstate.edu
Campus Sponsor:
Department of Mathematics
This is a learning seminar intended for discussion and questions throughout, and no prior knowledge is assumed!